This Technical Study on Making the Case for Resilient Drainage and Irrigation Systems in Guyana was developed by the Global Green Growth Institute (GGGI) and the National Drainage and Irrigation Authority (NDIA). The development of an effective drainage and irrigation strategic plan must be informed by extensive research into global best practices that demonstrate applicability in Guyana’s hydrological and climatic context. This involves assessing adaptive engineering solutions, nature-based interventions, and digital monitoring technologies that enhance resilience to extreme weather events. Such an approach ensures that Guyana’s Drainage & Irrigation framework is not only technically sound but also sustainable, adaptive, and responsive to evolving environmental and socio-economic challenges.